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Cefoxitin Sodium

Method: HPLC
Matrix: Medicine
Application No.: 101962
Columns: Spursil C18 3 μm 150 x 4.6 mm
Cat No.: 82018
Sample Pretreatment: System suitability solution: Dissolve 1.0 g of monobasic potassium phosphate and 1.8g of dibasic sodium phosphate in 900 mL of water. Adjust with phosphoric acid to a pH of 7.1, and dilute with water to 1 L to make a buffer. Dissolve 3 mg of Cefoxitin Sodium in 10 mL of buffer. Sonicate to aid dissolving. Use this solution within 5 h.
Conditions: Mobile phase: Acetonitrile, water, and glacial acetic acid (160: 840: 10).
Detector: UV 254 nm
Flow rate: 1.0 mL/min
Injection size: 2 µL
Column temp.: 30 ℃
Publisher: Dikma Technologies Inc.
Keyword: Cefoxitin Sodium, HPLC, Spursil C18
Abstract: Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. The experimental conditions follow guidelines from the USP43-NF38 monograph method.

 

Compound

Retention Time

(min)

Tailing Factor

Theoretical Plates

Cefoxitin Sodium

9.6

0.99

63860